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Creating Multiple Sequence Alignments

You can use the MSA editor to create and edit a multiple sequence alignment. You can use either the ClustalW, Muscle or T-Coffee algorithms to align several nucleotide or amino acid sequences simultaneously.

- both multiple and pairwise alignments can be displayed in standard MacVector text windows

- multiple alignments can be displayed as a high quality image that can be exported to other applications

- a consensus sequence can be displayed and saved as a new sequence.

- a guide tree of the sequence comparisons can be displayed, showing the relationships between sequences.

To perform an alignment, a nucleic acid or protein sequence must be the active window, and at least one other window of the same type must be open.

When you create an alignment from annotated protein sequences, then the Picture tab will display a colored box around any common domains.

Related Topics.

The MSA Editor

Picture tab

Domain coloring

Performing a ClustalW alignment

Performing a Muscle alignment

Performing a T-Coffee alignment

Displaying alignments

Guide tree